Co-Target(s) Information

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Target General Information
Co-Targets of This Target
References
Target General Information  Top
Target ID T26500 Target Info
Target Name Histamine H4 receptor (H4R)
Synonyms SP9144; Pfi-013; HH4R; H4 receptor; GPRv53; GPCR105; G protein-coupled receptor 105; AXOR35
Target Type Clinical trial Target
Gene Name HRH4
Biochemical Class GPCR rhodopsin
UniProt ID
HRH4_HUMAN
Co-Targets of This Target  Top
Co-Target Name Histamine H3 receptor (H3R) Clinical trial Target
UniProt ID HRH3_HUMAN
Gene Name HRH3
Synonyms Histamine receptor 3; HH3R; GPCR97; G-protein coupled receptor 97; G protein-coupled receptor 97
Representative Drug(s) PF-3893787 Drug Info Ki = 186.21 nM [1]
References  Top
REF 1 A novel series of histamine H4 receptor antagonists based on the pyrido[3,2-d]pyrimidine scaffold: comparison of hERG binding and target residence time with PF-3893787. Bioorg Med Chem Lett. 2013 May 1;23(9):2663-70.

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