COVID-19 Drug Information
Drug General Information | Top | |||
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Drug ID |
D05WJF
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Drug Name |
Defibrotide
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Synonyms |
STA-1474; Defibrotide sodium; UNII-E1942E7K32; E1942E7K32; Defibrotide; 1118915-78-8; SCHEMBL419884; CHEMBL3674153; JNWFIPVDEINBAI-UHFFFAOYSA-N; BDBM176684; BCP24376; BCP23704; 83712-60-1; US9120745, 3; Q27276739; Defibrotide sodium
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Drug Type |
Small molecular drug
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Indication | Coronavirus Disease 2019 (COVID-19) | Phase 2 | [1] | |
Other Indication | Hepatic veno-occlusive disease | Approved | [2] | |
Therapeutic Class |
Antiviral Agents
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Structure |
Download2D MOL |
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Formula |
C20H21N4O6P
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Canonical SMILES |
CC(C)C1=C(C=C(C(=C1)C2=NNC(=O)N2C3=CC4=C(C=C3)N(C=C4)C)O)OP(=O)(O)O
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InChI |
1S/C20H21N4O6P/c1-11(2)14-9-15(17(25)10-18(14)30-31(27,28)29)19-21-22-20(26)24(19)13-4-5-16-12(8-13)6-7-23(16)3/h4-11,25H,1-3H3,(H,22,26)(H2,27,28,29)
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InChIKey |
JNWFIPVDEINBAI-UHFFFAOYSA-N
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CAS Number |
CAS 1118915-78-8
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PubChem Compound ID |
References | Top | |||
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1 | ClinicalTrials.gov (NCT04335201) Defibrotide in COVID-19 Pneumonia. U.S. National Institutes of Health. | |||
2 | FDA Approved Drug Products from FDA Official Website. 2019. Application Number: (NDA) 208114 |
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