COVID-19 Drug Information
Drug General Information | Top | |||
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Drug ID |
D0D2PD
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Drug Name |
ABBV-744
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Synonyms |
ABBV744; UNII-9MX546E2SF; 9MX546E2SF; HWV; ABBV 744; SCHEMBL19463409
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Drug Type |
Small molecular drug
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Indication | Coronavirus Disease 2019 (COVID-19) | Investigative | [1] | |
Therapeutic Class |
Antiviral Agents
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Structure |
Download2D MOL |
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Formula |
C28H30FN3O4
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Canonical SMILES |
CCNC(=O)C1=CC2=C(N1)C(=O)N(C=C2C3=C(C=CC(=C3)C(C)(C)O)OC4=C(C=C(C=C4C)F)C)C
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InChI |
1S/C28H30FN3O4/c1-7-30-26(33)22-13-20-21(14-32(6)27(34)24(20)31-22)19-12-17(28(4,5)35)8-9-23(19)36-25-15(2)10-18(29)11-16(25)3/h8-14,31,35H,7H2,1-6H3,(H,30,33)
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InChIKey |
OEDSFMUSNZDJFD-UHFFFAOYSA-N
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CAS Number |
CAS 2138861-99-9
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PubChem Compound ID |
Target | Top | |||
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Target(s) | HUMAN bromodomain-containing protein 2 (BRD2) | Target Info | Inhibitor | [1] |
Early reports indicate that BRD2 interacts with SARS-CoV-2 envelope proteins. ABBV-744 is a BRD2 inhibitor and can interfere this interaction. |
References | Top | |||
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1 | Uncovering the Role of BRD2 in COVID-19. 2020-03-19 |
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