Drug General Information
Drug ID D0U4IV
Drug Name Elfamycin
Drug Resistance Mutations
Target Name Bacterial Elongation factor Tu (EF-Tu) Target Info
Gene Name EF-Tu
Uniprot ID EFTU_PEPD6
Species Peptoclostridium difficile
Reference Sequence MAKAKYERTKPHVNIGTIGHVDHGKTTLTAAITKTLYDRYQLGEAVDFANIDKAPEERER
GITISTAHVEYETPNRHYAHVDCPGHADYVKNMITGAAQMDGAILVCSATDGPMPQTREH
ILLSRQVGVPYIVVFLNKCDMVDDEELLELVEMEVRDLLTEYDFPGDDTPIVRGSALMAL
EDPKSEWGDKIVELFEQIDEYIPAPERDTDKPFLMPVEDVFSITGRGTVATGRVERGVLK
VQDEVELVGLTEAPRKVVVTGVEMFRKLLDQAQAGDNIGALLRGVQRNEIERGQVLAKTG
SVKAHTKFTAEVYVLKKEEGGRHTPFFDGYRPQFYFRTTDVTGACKLPEGIEMVMPGDNV
TMEVDLINSIVVEEGLRFSIREGGRTVASGVVATIIE [Peptoclostridium diff
icile]
Targeted Disease Clostridium difficile enterocolitis
Drug Resistance Mutations
Mutation info Missense: G261E [1]
References
REF 1 The comprehensive antibiotic resistance database. Antimicrob Agents Chemother. 2013 Jul;57(7):3348-57.

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