Drug General Information
Drug ID
D0D9HW
Former ID
DAP000700
Drug Name
Tenofovir
Synonyms
Apropovir; PMPA; TFV; Tenefovir; GS 1275; GS 1278; GS1278; GNA & Tenofovir; HHA & Tenofovir; KS-5021; Viread (TN); Viread, Tenofovir; D,L-Tenofovir; PMPA-(R); Phosphonic acid, [[2-(6-amino-9H-purin-9; [(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethylphosphonic acid; Phosphonic acid, [[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-(9CI); Phosphonic acid, [[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-& Galanthus nivalis agglutinin (GNA); Phosphonic acid, [[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-& Hippeastrum hybrid agglutinin(HHA); (R)-9-(2-Phosphonomethoxypropyl)adenine; (R)-9-(2-Phosphonylmethoxypropyl)adenine; (R)-PMPA
Drug Type
Small molecular drug
Indication Human immunodeficiency virus infection [ICD-11: 1C62; ICD-9: 279.3] Approved [1]
Therapeutic Class
Anti-HIV Agents
Company
Gilead Sciences
Structure
Download
2D MOL

3D MOL

Formula
C9H14N5O4P
Canonical SMILES
CC(CN1C=NC2=C1N=CN=C2N)OCP(=O)(O)O
InChI
1S/C9H14N5O4P/c1-6(18-5-19(15,16)17)2-14-4-13-7-8(10)11-3-12-9(7)14/h3-4,6H,2,5H2,1H3,(H2,10,11,12)(H2,15,16,17)/t6-/m1/s1
InChIKey
SGOIRFVFHAKUTI-ZCFIWIBFSA-N
CAS Number
CAS 147127-20-6
PubChem Compound ID
PubChem Substance ID
SuperDrug ATC ID
J05AF07
SuperDrug CAS ID
cas=201341051
Drug Resistance Mutation (DRM)
DRM DRM Info
Target and Pathway
Target(s) Human immunodeficiency virus Reverse transcriptase (HIV RT) Target Info Inhibitor [2]
References
REF 1 Anti-hepatitis B virus activity in vitro of combinations of tenofovir with nucleoside/nucleotide analogues. Antivir Chem Chemother. 2009;19(4):165-76.
REF 2 Antiviral drugs in current clinical use. J Clin Virol. 2004 Jun;30(2):115-33.

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