Drug General Information
Drug ID
D0P3JU
Former ID
DAP000240
Drug Name
Clorazepate
Synonyms
Chlorazepate; Tranxene; Cchlorazepic acid; Chlorazepic acid; Clorazepate dipotassium; Clorazepic acid; Clorazepic acid [BAN]; Gen-xene; Novo-Clopate; Tranxene (Cherazepate dipotasium); Tranxene (TN); Novo-Clopate (TN); (Chloromethyl)(dimethyl)(tridecyloxy)silane; 7-Chloro-2,3-dihydro-2,2-dihydroxy-5-phenyl-1H-1,4-benzodiazepine-3-carboxylic acid; 7-chloro-2-oxo-5-phenyl-1,3-dihydro-1,4-benzodiazepine-3-carboxylic acid; 7-chloro-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepine-3-carboxylic acid
Drug Type
Small molecular drug
Indication Anxiety disorder [ICD-11: 6B00-6B0Z] Approved [1], [2]
Therapeutic Class
Hypnotics and Sedatives
Company
Taro Pharmaceutical Industries Ltd
Structure
Download
2D MOL

3D MOL

Formula
C16H11ClN2O3
InChI
1S/C16H11ClN2O3/c17-10-6-7-12-11(8-10)13(9-4-2-1-3-5-9)19-14(16(21)22)15(20)18-12/h1-8,14H,(H,18,20)(H,21,22)
InChIKey
XDDJGVMJFWAHJX-UHFFFAOYSA-N
CAS Number
CAS 23887-31-2
PubChem Compound ID
PubChem Substance ID
SuperDrug ATC ID
N05BA05
Target and Pathway
Target(s) Translocator protein (TSPO) Target Info Modulator [3]
KEGG Pathway Neuroactive ligand-receptor interaction
HTLV-I infection
References
REF 1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7548).
REF 2 FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (ANDA) 071852.
REF 3 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.

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