Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D01ZOG
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| Former ID |
DNAP001297
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| Drug Name |
Difluprednate
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| Synonyms |
Durezol (TN)
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| Drug Type |
Small molecular drug
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| Indication | Ocular pain [ICD-11: MC18; ICD-10: R52, G89; ICD-9: 338780] | Approved | [1], [2], [3] | |
| Company |
Sirion
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| Structure |
 |
Download2D MOL |
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| Formula |
C27H34F2O7
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| Canonical SMILES |
CCCC(=O)OC1(CCC2C1(CC(C3(C2CC(C4=CC(=O)C=CC43C)F)F)O)C)C(=O)COC(=O)C
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| InChI |
1S/C27H34F2O7/c1-5-6-23(34)36-26(22(33)14-35-15(2)30)10-8-17-18-12-20(28)19-11-16(31)7-9-24(19,3)27(18,29)21(32)13-25(17,26)4/h7,9,11,17-18,20-21,32H,5-6,8,10,12-14H2,1-4H3/t17-,18-,20-,21-,24-,25-,26-,27-/m0/s1
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| InChIKey |
WYQPLTPSGFELIB-JTQPXKBDSA-N
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| CAS Number |
CAS 23674-86-4
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| PubChem Compound ID | ||||
| PubChem Substance ID |
583085, 856020, 7848329, 7979081, 10299429, 14811237, 16650119, 24894018, 36887084, 51530976, 56422387, 56423155, 57404556, 71840218, 91703898, 99443292, 103771485, 104630981, 124799718, 134995746, 137239501, 139999922, 144206181, 160967909, 162184652, 163835796, 164178105, 165235879, 175268498, 179150205, 187051777, 210275696, 210281355, 223441703, 226396555, 252359500
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| ChEBI ID |
CHEBI:31485
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| ADReCS Drug ID | BADD_D00667 | |||
| SuperDrug ATC ID |
D07AC19
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Phospholipase A2 inhibitory protein (PA2IP) | Target Info | Agonist | [2], [3] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7474). | |||
| REF 2 | 2008 FDA drug approvals. Nat Rev Drug Discov. 2009 Feb;8(2):93-6. | |||
| REF 3 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | |||
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