Drug General Information
Drug ID	D06VTI
Drug Name	Macrocycle derivative 1
Synonyms	PMID30107136-Compound-Example65
Drug Type	Small molecule immunotherapy
Indication	Hepatitis [ICD-11: DB97.Z]		Patented	[1]
	Human immunodeficiency virus infection [ICD-11: 1C62; ICD-9: 42]		Patented	[1]
	Infectious disease [ICD-11: 1A00-CA43.1; ICD-10: A00-B99; ICD-9: 001-139]		Patented	[1]
	Solid tumour/cancer [ICD-11: 2A00-2F9Z; ICD-10: C76-C80; ICD-9: 140-229]		Patented	[1]
Company	Bristol-Myers Squibb Company
Structure
Target and Pathway
Target(s)	CD80-PD-L1 interaction (CD80/PD-L1 PPI)	Target Info	Inhibitor	[1]
	PD-1-PD-L1 interaction (PD-1/PD-L1 PPI)	Target Info	Inhibitor	[1]
Target's Patent Info	CD80-PD-L1 interaction (CD80/PD-L1 PPI)	Target's Patent Info		[1]
	PD-1-PD-L1 interaction (PD-1/PD-L1 PPI)	Target's Patent Info		[1]
References
REF 1	A patent review on PD-1/PD-L1 antagonists: small molecules, peptides, and macrocycles (2015-2018).Expert Opin Ther Pat. 2018 Sep;28(9):665-678.

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