Drug Information
Drug General Information | Top | |||
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Drug ID |
D07JAG
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Former ID |
DIB008103
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Drug Name |
Upadacitinib
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Synonyms |
ABT-494
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Indication | Rheumatoid arthritis [ICD-11: FA20; ICD-9: 729] | Approved | [1] | |
Psoriatic arthritis [ICD-11: FA21; ICD-9: 696] | Phase 3 | [2] | ||
Atopic dermatitis [ICD-11: EA80; ICD-10: L20; ICD-9: 691.8, 692.9] | Phase 2 | [2] | ||
Crohn disease [ICD-11: DD70; ICD-10: K50, K50.9; ICD-9: 555] | Phase 2 | [3] | ||
Ulcerative colitis [ICD-11: DD71; ICD-9: 556] | Phase 2 | [3] | ||
Company |
Abbvie
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Structure |
Download2D MOL |
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Formula |
C17H19F3N6O
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Canonical SMILES |
CCC1CN(CC1C2=CN=C3N2C4=C(NC=C4)N=C3)C(=O)NCC(F)(F)F
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InChI |
1S/C17H19F3N6O/c1-2-10-7-25(16(27)24-9-17(18,19)20)8-11(10)13-5-22-14-6-23-15-12(26(13)14)3-4-21-15/h3-6,10-11,21H,2,7-9H2,1H3,(H,24,27)/t10-,11+/m1/s1
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InChIKey |
WYQFJHHDOKWSHR-MNOVXSKESA-N
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CAS Number |
CAS 1310726-60-3
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PubChem Compound ID | ||||
ADReCS Drug ID | BADD_D02407 |
References | Top | |||
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REF 1 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health Human Services. 2019 | |||
REF 2 | Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA) | |||
REF 3 | Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA) |
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