Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0FD0H
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| Former ID |
DAP000200
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| Drug Name |
Aminocaproic Acid
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| Synonyms |
6-Aminohexanoic acid; 6-aminohexanoic acid; 6-Aminocaproic acid; aminocaproic acid; 60-32-2; amicar; Epsikapron; Caprocid; Capramol; Epsamon; EACA; Caprolisin; Acepramin; Hemocaprol; Epsicapron; Respramin; Amikar; EPSILON-AMINOCAPROIC ACID; Hexanoic acid, 6-amino-; Epsilcapramin; Aminokapron; Caplamin; Acepramine; Capracid; Hemopar; Ipsilon; Afibrin; Atsemin; Hepin; Epsilon S; Aminocaproic; Capralense; epsilon-Leucine; EACS; epsilon-Norleucine; epsilcapramine; 6-Amino-n-hexanoic acid; omega-Aminocaproic acid; epsilon-Aminohexanoic acid; 6-amino-hexanoic acid; ACS; Amicar; Aminocaproate; Capranol; Caproamin; Epsicaprom; Epsilcapramine; Hemopar;Hepin; Acide aminocaproique; Acide aminocaproique [French]; Acide aminocaproque; Acido aminocaproico; Acidum aminocaproicum; Acidum aminocaproicum [Latin]; Aminocaproic Acid In Plastic Container; Aminocaproic Acids; Aminohexanoic acid; Eaca kabi; Epsilon Aminocaproic Acid; A 7824; CL 10304; CY 116; CY116; JD 177; Acide aminocaproique [INN-French]; Acido aminocaproico [DCIT,Spanish]; Acido aminocaproico [INN-Spanish]; Acidum aminocaproicum [INN-Latin]; Amicar (TN); Aminocaproic acid (USP); CL-10304; CY-116; Epsilon-Ahx; Epsilon-Aminocaproic acid; Epsilon-Aminocapronsaeure; Epsilon-Aminohexanoic acid; Epsilon-Leucine; Epsilon-Norleucine; Epsilon-aminocaproate; Epsilon-aminocapronzuur; Fullevir (TN); Kyselina omega-aminokapronova; Kyselina omega-aminokapronova [Czech]; Omega-Aminocaproic acid; Omega-Aminohexanoic acid; S04-0132; Acid, 6-Aminocaproic; Acid, 6-Aminohexanoic; Acid, epsilon-Aminocaproic; Aminocaproic acid (USP/INN); Aminocaproic acid [USAN:BAN:INN]; Aminocaproic acid [USAN:INN:BAN]; Epsilon-Aminocaproic acid (JAN); HEXANOIC ACID,6-AMINO; Epsilon-Amino-n-caproic acid; Epsilon-Amino-n-hexanoic acid; Amicar, A-amino caproic acid, A-Ahx, 6-aminohexanoic acid, Aminocaproic acid; 6 Aminocaproic Acid; 6 Aminohexanoic Acid; 6-amino-n-caproate; 6-amino-n-caproic acid; 6-aminohexanoate; 6-Amino Hexanoic Acid
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| Drug Type |
Small molecular drug
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| Indication | Bleeding disorder [ICD-11: GA20-GA21] | Approved | [1] | |
| Postoperative hemorrhage [ICD-11: NE81.0Z; ICD-9: 459] | Approved | [2], [3] | ||
| Therapeutic Class |
Antifibrinolytic Agents
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| Company |
Intelfarm Co.
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| Structure |
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Download2D MOL |
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| Formula |
C6H13NO2
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| Canonical SMILES |
C(CCC(=O)O)CCN
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| InChI |
1S/C6H13NO2/c7-5-3-1-2-4-6(8)9/h1-5,7H2,(H,8,9)
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| InChIKey |
SLXKOJJOQWFEFD-UHFFFAOYSA-N
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| CAS Number |
CAS 60-32-2
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| PubChem Compound ID | ||||
| PubChem Substance ID |
5420, 87073, 127775, 471451, 588079, 608071, 3131896, 4656524, 7847228, 7885665, 7885778, 7978686, 8143494, 8149196, 8150692, 10529215, 11110778, 11110779, 11133308, 11335726, 11360965, 11362812, 11365374, 11367936, 11373725, 11376098, 11461937, 11466988, 11468108, 11483938, 11486845, 11487947, 11491958, 11493852, 15119949, 17404645, 24278238, 24438930, 24701164, 24890662, 26522162, 26611600, 26679239, 26703793, 26717434, 26718589, 26747439, 26747440, 46391648, 46394356
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| ChEBI ID |
CHEBI:16586
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| ADReCS Drug ID | BADD_D00106 | |||
| SuperDrug ATC ID |
B02AA01
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| SuperDrug CAS ID |
cas=000060322
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| References | Top | |||
|---|---|---|---|---|
| REF 1 | The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954. | |||
| REF 2 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6574). | |||
| REF 3 | FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (ANDA) 071192. | |||
| REF 4 | The blockage of the high-affinity lysine binding sites of plasminogen by EACA significantly inhibits prourokinase-induced plasminogen activation. Biochim Biophys Acta. 2002 Apr 29;1596(2):182-92. | |||
| REF 5 | Analysis of plasmin binding and urokinase activation of plasminogen bound to the Heymann nephritis autoantigen, gp330. Arch Biochem Biophys. 1992 Dec;299(2):255-60. | |||
| REF 6 | How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6. | |||
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