Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0J1UA
|
|||
| Former ID |
DIB003009
|
|||
| Drug Name |
Elosulfase alfa
|
|||
| Synonyms |
Vimizim
Click to Show/Hide
|
|||
| Indication | Mucopolysaccharidosis [ICD-11: 5C56.3] | Approved | [1], [2] | |
| Company |
Biomarin
|
|||
| ADReCS Drug ID | BADD_D00758 | |||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | N-acetylgalactosamine 6 sulfatase (GALNS) | Target Info | Modulator | [2], [3] |
| BioCyc | Chondroitin sulfate degradation (metazoa) | |||
| KEGG Pathway | Glycosaminoglycan degradation | |||
| Metabolic pathways | ||||
| Lysosome | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7392). | |||
| REF 2 | 2014 FDA drug approvals. Nat Rev Drug Discov. 2015 Feb;14(2):77-81. | |||
| REF 3 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.