Drug General Information
Drug ID
D0P3EG
Drug Name
1,3,4-oxadiazole derivative 2
Synonyms
PMID30107136-Compound-Example38
Drug Type
Small molecule immunotherapy
Indication Hepatitis [ICD-11: DB97.Z] Patented [1]
Human immunodeficiency virus infection [ICD-11: 1C62; ICD-9: 42] Patented [1]
Infectious disease [ICD-11: 1A00-CA43.1; ICD-10: A00-B99; ICD-9: 001-139] Patented [1]
Solid tumour/cancer [ICD-11: 2A00-2F9Z; ICD-10: C76-C80; ICD-9: 140-229] Patented [1]
Company
AURIGENE DISCOVERY TECHNOLOGIES LIMITED
Structure
Download
2D MOL

3D MOL

Formula
C22H25N5O5S
InChIKey
JHNLLRMWPHPFLP-SFHVURJKSA-N
PubChem Compound ID
Target and Pathway
Target(s) Programmed cell death protein 1 (PD-1) Target Info Inhibitor [1]
Target's Patent Info Programmed cell death protein 1 (PD-1) Target's Patent Info [1]
KEGG Pathway Cell adhesion molecules (CAMs)
T cell receptor signaling pathway
Reactome PD-1 signaling
WikiPathways T-Cell Receptor and Co-stimulatory Signaling
Costimulation by the CD28 family
References
REF 1 A patent review on PD-1/PD-L1 antagonists: small molecules, peptides, and macrocycles (2015-2018).Expert Opin Ther Pat. 2018 Sep;28(9):665-678.

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