Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0QC3M
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| Former ID |
DIB010809
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| Drug Name |
Amorolfine
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| Synonyms |
Loceryl; Pekiron; MT-861; Amorolfine (cream, onychomycosis); Ro-14-4767; Amorolfine (cream, onychomycosis), Roche; Ro-14-4767/002
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| Drug Type |
Small molecular drug
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| Indication | Onychomycosis [ICD-11: EE12.1] | Approved | [1], [2] | |
| Company |
F Hoffmann-La Roche Ltd
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| Structure |
 |
Download2D MOL |
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| Formula |
C21H35NO
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| Canonical SMILES |
CCC(C)(C)C1=CC=C(C=C1)CC(C)CN2CC(OC(C2)C)C
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| InChI |
1S/C21H35NO/c1-7-21(5,6)20-10-8-19(9-11-20)12-16(2)13-22-14-17(3)23-18(4)15-22/h8-11,16-18H,7,12-15H2,1-6H3/t16?,17-,18+
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| InChIKey |
MQHLMHIZUIDKOO-AYHJJNSGSA-N
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| CAS Number |
CAS 78613-35-1
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| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:599440
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| ADReCS Drug ID | BADD_D00127 | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | |||
| REF 2 | ClinicalTrials.gov (NCT01014637) Efficacy, Safety and Cost-effectiveness of a Sequential Therapy With RV4104A Ointment, Ciclopiroxolamine Cream and Ciclopirox Film-forming Solution Compared With Amorolfine Nail Lacquer in Dermatophytic Onychomycosis. U.S. National Institutes of Health. | |||
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