Target's General Information
Target ID T00938
Target Name Melanoma antigen gp75 (TYRP1)
Synonyms Tyrosinaserelated protein 1; TYRP1; TRP; Glycoprotein 75; Catalase B; 5,6dihydroxyindole2carboxylic acid oxidase
Target Type Clinical trial
Gene Name TYRP1
Biochemical Class Tyrosinase
UniProt ID TYRP1_HUMAN
Target's Expression Profile in Disease Related Tissue between Patients and Normal People
Disease Melanoma
Example drug Flanvotumab Phase 1 [1], [2], [3]
Tissue Skin
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual Fold-change: 0.53
Z-score: 0.21
P-value: 7.82E-01
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
Target's Expression Profile across Various Tissues of Healthy Individual
References
REF 1 ClinicalTrials.gov (NCT01137006) An Open-Label, Dose-Escalation Study of IMC-20D7S In Patients With Malignant Melanoma. U.S. National Institutes of Health.
REF 2 Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41.
REF 3 NCBI GEO: archive for functional genomics data sets--update. Nucleic Acids Res. 2013 Jan;41(Database issue):D991-5.

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