Target's General Information
Target ID T08910
Target Name GABA(A) receptor gamma-2 (GABRG2)
Synonyms Gamma-aminobutyric acid receptor subunit gamma-2; GABA(A) receptor subunit gamma-2
Target Type Successful
Gene Name GABRG2
Biochemical Class Neurotransmitter receptor
UniProt ID GBRG2_HUMAN
Target's Expression Profile in Disease Related Tissue between Patients and Normal People
Disease Epilepsy
Example drug ZK-93423 Phase 3 [1], [2], [3], [4]
Tissue Peritumoral cortex tissue
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
Target's Expression Profile across Various Tissues of Healthy Individual
References
REF 1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4346).
REF 2 Abecarnil enhances GABA-induced currents in acutely isolated cerebellar Purkinje cells. Neuropharmacology. 1995 Feb;34(2):157-63.
REF 3 Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41.
REF 4 NCBI GEO: archive for functional genomics data sets--update. Nucleic Acids Res. 2013 Jan;41(Database issue):D991-5.

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