| Target's General Information |
| Target ID |
T11253 |
| Target Name |
HSPB1 messenger RNA (HSPB1 mRNA) |
| Synonyms |
Stress-responsive protein 27 (mRNA); SRP27 (mRNA); HspB1 (mRNA); Heat shock protein beta-1 (mRNA); Heat shock 27 kDa protein (mRNA); HSP28 (mRNA); HSP 27 (mRNA); Estrogen-regulated 24 kDa protein (mRNA); 28 kDa heat shock protein (mRNA) |
| Target Type |
Discontinued |
| Gene Name |
HSPB1 |
| Biochemical Class |
mRNA target |
| UniProt ID |
HSPB1_HUMAN |
| Target's Expression Profile in Disease Related Tissue between Patients and Normal People |
| Disease |
Breast cancer |
| Tissue |
Breast tissue |
| Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual |
Fold-change: 0.96
Z-score: 1.29
P-value: 3.31E-42
|
| Level of differential expression between the patients in the disease section of the tissue section of the tissue adjacent to the disease section |
Fold-change: 0.86
Z-score: 0.65
P-value: 5.35E-07
|
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles of the patients in the normal section of the tissue adjacent to the disease section
Target gene expression profiles in the tissue of healthy individual
|
| Disease |
Lung cancer |
| Tissue |
Lung tissue |
| Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual |
Fold-change: 0.22
Z-score: 0.54
P-value: 4.18E-08
|
| Level of differential expression between the patients in the disease section of the tissue section of the tissue adjacent to the disease section |
Fold-change: 0.23
Z-score: 0.38
P-value: 2.61E-06
|
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles of the patients in the normal section of the tissue adjacent to the disease section
Target gene expression profiles in the tissue of healthy individual
|
| Disease |
Ovarian cancer |
| Tissue |
Ovarian tissue |
| Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual |
Fold-change: 0.46
Z-score: 0.54
P-value: 3.12E-01
|
| Level of differential expression between the patients in the disease section of the tissue section of the tissue adjacent to the disease section |
Fold-change: 1.32
Z-score: 1.19
P-value: 1.69E-02
|
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles of the patients in the normal section of the tissue adjacent to the disease section
Target gene expression profiles in the tissue of healthy individual
|
| Disease |
Prostate cancer |
| Tissue |
Prostate |
| Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual |
Fold-change: -0.64
Z-score: -1.66
P-value: 6.15E-13
|
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
|
| Disease |
Rheumatoid arthritis |
| Tissue |
Synovial tissue |
| Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual |
Fold-change: 1.68
Z-score: 2.24
P-value: 1.49E-03
|
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
|
| Disease |
Bladder cancer |
| Tissue |
Bladder tissue |
| Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual |
Fold-change: -0.48
Z-score: -2.45
P-value: 3.30E-05
|
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
|
| References |
| REF 1 |
NCBI GEO: archive for functional genomics data sets--update. Nucleic Acids Res. 2013 Jan;41(Database issue):D991-5.
|
