Target expression details
| Target's General Information | |||||
|---|---|---|---|---|---|
| Target ID | T30635 | ||||
| Target Name | C-X-C motif chemokine 10 (CXCL10) | ||||
| Synonyms | Small-inducible cytokine B10; SCYB10; IP-10; INP10; Gamma-IP10; 10 kDa interferon gamma-induced protein | ||||
| Target Type | Clinical trial | ||||
| Gene Name | CXCL10 | ||||
| Biochemical Class | Cytokine: CXC chemokine | ||||
| UniProt ID | CXL10_HUMAN | ||||
| Target's Expression Profile in Disease Related Tissue between Patients and Normal People | |||||
| Disease | Ulcerative colitis | ||||
| Example drug | Anti-IP10 | Phase 2 | [1], [2], [3] | ||
| Tissue | Colon mucosal tissue | ||||
| Level of differential expression between the patients in the disease section of the tissue section of the tissue adjacent to the disease section |
Fold-change: 0.65 Z-score: 0.27 P-value: 6.07E-01 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
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| Target's Expression Profile across Various Tissues of Healthy Individual | |||||
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| References | |||||
| REF 1 | ClinicalTrials.gov (NCT01466374) Induction and Maintenance Study of BMS-936557 in Patients With Moderate to Severely Active Crohn's Disease. U.S. National Institutes of Health. | ||||
| REF 2 | Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41. | ||||
| REF 3 | NCBI GEO: archive for functional genomics data sets--update. Nucleic Acids Res. 2013 Jan;41(Database issue):D991-5. | ||||
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