Target's General Information
Target ID T54761
Target Name Myelin basic protein (MBP)
Synonyms Myelin membrane encephalitogenic protein; Myelin A1 protein
Target Type Clinical trial
Gene Name MBP
UniProt ID MBP_HUMAN
Target's Expression Profile in Disease Related Tissue between Patients and Normal People
Disease Multiple sclerosis
Example drug BHT-3009 Phase 2 [1], [2], [3]
Tissue Spinal cord
Level of differential expression between the patients in the disease section of the tissue section of the tissue adjacent to the disease section Fold-change: 0.02
Z-score: 0.18
P-value: 7.10E-01
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles of the patients in the normal section of the tissue adjacent to the disease section
Target gene expression profiles in the tissue of healthy individual
Target's Expression Profile across Various Tissues of Healthy Individual
References
REF 1 ClinicalTrials.gov (NCT00382629) BHT-3009 Immunotherapy in Relapsing Remitting Multiple Sclerosis. U.S. National Institutes of Health.
REF 2 Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41.
REF 3 NCBI GEO: archive for functional genomics data sets--update. Nucleic Acids Res. 2013 Jan;41(Database issue):D991-5.

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