Target expression details
| Target's General Information | |||||
|---|---|---|---|---|---|
| Target ID | T89515 | ||||
| Target Name | Polypeptide deformylase (PDF) | ||||
| Synonyms | |||||
| Target Type | Successful | ||||
| Gene Name | |||||
| Biochemical Class | CH-NH donor oxidoreductase | ||||
| UniProt ID | DYR_HUMAN | ||||
| Target's Expression Profile in Disease Related Tissue between Patients and Normal People | |||||
| Disease | Acute myelocytic leukemia | ||||
| Example drug | Aminopterin | Withdrawn from market | [1], [2] | ||
| Tissue | Bone marrow | ||||
| Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual |
Fold-change: -0.54 Z-score: -0.86 P-value: 8.87E-16 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
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| Disease | Rheumatoid arthritis | ||||
| Tissue | Synovial tissue | ||||
| Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual |
Fold-change: 0.38 Z-score: 1.46 P-value: 1.08E-02 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
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| Disease | Bladder cancer | ||||
| Tissue | Bladder tissue | ||||
| Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual |
Fold-change: 0.97 Z-score: 3.88 P-value: 5.11E-06 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
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| References | |||||
| REF 1 | Drug information of Aminopterin, Health Canada, 2007. | ||||
| REF 2 | NCBI GEO: archive for functional genomics data sets--update. Nucleic Acids Res. 2013 Jan;41(Database issue):D991-5. | ||||
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