miRNA General Information
miRNA Mature ID hsa-miR-193b-3p
miRNA Stemloop AC MI0003137
miRNA Stemloop ID hsa-mir-193b
Sequence aacuggcccucaaagucccgcu
TTD Target(s) Regulated by This miRNA Estrogen receptor (ESR) Successful Target Target Info [1]
Tyrosine-protein kinase Kit (KIT) Successful Target Target Info [2]
Urokinase-type plasminogen activator (PLAU) Successful Target Target Info [3]
Mothers against decapentaplegic homolog 3 (SMAD3) Successful Target Target Info [4]
Induced myeloid leukemia cell differentiation protein Mcl-1 (MCL1) Clinical trial Target Target Info [5]
G1/S-specific cyclin-D1 (CCND1) Clinical trial Target Target Info [6]
DNA repair protein RAD51 homolog 1 (RAD51) Clinical trial Target Target Info [6]
Protein C-ets-1 (ETS1) Literature-reported Target Target Info [7]
Protein(s) Regulated by This miRNA 14-3-3 protein zeta/delta Regulated Protein [8]
Aldo-keto reductase family 1 member C2 Regulated Protein [8]
Neurofibromin Regulated Protein [9]
Proline-rich acidic protein 1 Regulated Protein [10]
Protein max Regulated Protein [11]
Serine hydroxymethyltransferase, mitochondrial Regulated Protein [8]
REF 1 The micro-ribonucleic acid (miRNA) miR-206 targets the human estrogen receptor-alpha (ERalpha) and represses ERalpha messenger RNA and protein expression in breast cancer cell lines. Mol Endocrinol. 2007 May;21(5):1132-47.
REF 2 A quantitative analysis of CLIP methods for identifying binding sites of RNA-binding proteins. Nat Methods. 2011 May 15;8(7):559-64.
REF 3 MicroRNA-23b mediates urokinase and c-met downmodulation and a decreased migration of human hepatocellular carcinoma cells. FEBS J. 2009 Jun;276(11):2966-82.
REF 4 miR-193b promotes cell proliferation by targeting Smad3 in human glioma. J Neurosci Res. 2014 May;92(5):619-26.
REF 5 Hepatitis C virus proteins modulate microRNA expression and chemosensitivity in malignant hepatocytes. Clin Cancer Res. 2010 Feb 1;16(3):957-66.
REF 6 MicroRNA-193b represses cell proliferation and regulates cyclin D1 in melanoma. Am J Pathol. 2010 May;176(5):2520-9.
REF 7 MicroRNA-193b regulates proliferation, migration and invasion in human hepatocellular carcinoma cells. Eur J Cancer. 2010 Oct;46(15):2828-36.
REF 8 Identification of miR-193b targets in breast cancer cells and systems biological analysis of their functional impact.Mol Cell Proteomics. 2011 Jul;10(7):M110.005322.
REF 9 MicroRNA-193b enhances tumor progression via down regulation of neurofibromin 1.PLoS One. 2013;8(1):e53765.
REF 10 Impaired MicroRNA Processing Facilitates Breast Cancer Cell Invasion by Upregulating Urokinase-Type Plasminogen Activator Expression.Genes Cancer. 2011 Feb;2(2):140-50.
REF 11 miR-193b/365a cluster controls progression of epidermal squamous cell carcinoma.Carcinogenesis. 2014 May;35(5):1110-20.

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