miRNA Details
| miRNA General Information | |||||
|---|---|---|---|---|---|
| miRNA Mature ID | hsa-miR-203a-5p | ||||
| miRNA Stemloop AC | MI0000283 | ||||
| miRNA Stemloop ID | hsa-mir-203a | ||||
| Sequence | agugguucuuaacaguucaacaguu | ||||
| TTD Target(s) Regulated by This miRNA | Matrix metalloproteinase-2 (MMP-2) | Successful Target | Target Info | [1] | |
| Cyclin-dependent kinase 6 (CDK6) | Successful Target | Target Info | [1] | ||
| Matrix metalloproteinase-7 (MMP-7) | Successful Target | Target Info | [1] | ||
| Matrix metalloproteinase-9 (MMP-9) | Clinical trial Target | Target Info | [1] | ||
| CDK inhibitor 1B p27Kip1 (CDKN1B) | Literature-reported Target | Target Info | [1] | ||
| Melanoma differentiation-associated protein 6 (CDKN1A) | Literature-reported Target | Target Info | [1] | ||
| Secreted frizzled related protein-4 (SFRP4) | Literature-reported Target | Target Info | [2] | ||
| Protein(s) Regulated by This miRNA | G1/S-specific cyclin-D2 | Regulated Protein | [1] | ||
| Ras-related protein Rap-1A | Regulated Protein | [4] | |||
| Transmembrane 4 L6 family member 1 | Regulated Protein | [2] | |||
| UV radiation resistance-associated gene protein | Regulated Protein | [6] | |||
| References | |||||
| REF 1 | MicroRNA-203 Regulates Growth and Metastasis of Breast Cancer. Cell Physiol Biochem. 2015;37(1):35-42. | ||||
| REF 2 | miR-203 inhibits arecoline-induced epithelial-mesenchymal transition by regulating secreted frizzled-related protein 4 and transmembrane-4 L six family member 1 in oral submucous fibrosis. Oncol Rep. 2015 Jun;33(6):2753-60. | ||||
| REF 3 | MicroRNA-203 Regulates Growth and Metastasis of Breast Cancer. Cell Physiol Biochem. 2015;37(1):35-42. | ||||
| REF 4 | MiR-203 down-regulates Rap1A and suppresses cell proliferation, adhesion and invasion in prostate cancer.J Exp Clin Cancer Res. 2015 Jan 31;34:8. | ||||
| REF 5 | miR-203 inhibits arecoline-induced epithelial-mesenchymal transition by regulating secreted frizzled-related protein 4 and transmembrane-4 L six family member 1 in oral submucous fibrosis. Oncol Rep. 2015 Jun;33(6):2753-60. | ||||
| REF 6 | RBM28, a protein deficient in ANE syndrome, regulates hair follicle growth via miR-203 and p63.Exp Dermatol. 2015 Aug;24(8):618-22. | ||||
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