miRNA General Information
miRNA Mature ID hsa-miR-26a-1-3p
miRNA Stemloop AC MI0000083
miRNA Stemloop ID hsa-mir-26a-1
Sequence ccuauucuugguuacuugcacg
TTD Target(s) Regulated by This miRNA Apoptosis regulator Bcl-2 (BCL-2) Successful Target Target Info [1]
Glycogen synthase kinase-3 beta (GSK-3B) Clinical trial Target Target Info [2]
Protein kinase C delta (PRKCD) Clinical trial Target Target Info [2]
Caspase-3 (CASP3) Clinical trial Target Target Info [1]
Cellular tumor antigen p53 (TP53) Clinical trial Target Target Info [1]
X-linked inhibitor of apoptosis protein (XIAP) Clinical trial Target Target Info [1]
M-phase inducer phosphatase 1 (MPIP1) Literature-reported Target Target Info [1]
Phosphatase and tensin homolog (PTEN) Literature-reported Target Target Info [3]
Tyrosine-protein kinase ABL2 (ABL2) Literature-reported Target Target Info [1]
Transcription factor 7-like 2 (TCF7L2) Literature-reported Target Target Info [2]
G1/S-specific cyclin-E2 (CCNE2) Literature-reported Target Target Info [1]
Protein(s) Regulated by This miRNA Apoptotic protease-activating factor 1 Regulated Protein [1]
Long-chain-fatty-acid--CoA ligase 3 Regulated Protein [2]
Long-chain-fatty-acid--CoA ligase 4 Regulated Protein [2]
Phosphoenolpyruvate carboxykinase, cytosolic [GTP] Regulated Protein [2]
References
REF 1 The Antitumor Effect of Metformin Is Mediated by miR-26a in Breast Cancer. Int J Mol Sci. 2016 Aug 10;17(8). pii: E1298.
REF 2 MicroRNA-26a regulates insulin sensitivity and metabolism of glucose and lipids. J Clin Invest. 2015 Jun;125(6):2497-509.
REF 3 Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps. Nature. 2009 Jul 23;460(7254):479-86.
REF 4 The Antitumor Effect of Metformin Is Mediated by miR-26a in Breast Cancer. Int J Mol Sci. 2016 Aug 10;17(8). pii: E1298.
REF 5 MicroRNA-26a regulates insulin sensitivity and metabolism of glucose and lipids. J Clin Invest. 2015 Jun;125(6):2497-509.

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