miRNA General Information
miRNA Mature ID hsa-miR-27a-5p
miRNA Stemloop AC MI0000085
miRNA Stemloop ID hsa-mir-27a
Sequence agggcuuagcugcuugugagca
TTD Target(s) Regulated by This miRNA Epidermal growth factor receptor (EGFR) Successful Target Target Info [1]
Peroxisome proliferator-activated receptor alpha (PPARA) Successful Target Target Info [2]
Synaptosomal-associated protein 25 (SNAP25) Successful Target Target Info [3]
RAC-alpha serine/threonine-protein kinase (AKT1) Successful Target Target Info [4]
Gremlin-1 (Gremlin-1) Patented-recorded Target Target Info [2]
Protein(s) Regulated by This miRNA Max-interacting protein 1 Regulated Protein [5]
Phosphatidylethanolamine-binding protein 1 Regulated Protein [6]
Secreted frizzled-related protein 1 Regulated Protein [7]
Thioredoxin, mitochondrial Regulated Protein [3]
References
REF 1 MicroRNA-27a functions as a tumor suppressor in renal cell carcinoma by targeting epidermal growth factor receptor. Oncol Lett. 2016 Jun;11(6):4217-4223.
REF 2 miR-27a attenuates adipogenesis and promotes osteogenesis in steroid-induced rat BMSCs by targeting PPAR and GREM1. Sci Rep. 2016 Dec 2;6:38491.
REF 3 MicroRNA miR-27 Inhibits Adenovirus Infection by Suppressing the Expression of SNAP25 and TXN2. J Virol. 2017 May 26;91(12). pii: e00159-17.
REF 4 Coordinated targeting of the EGFR signaling axis by microRNA-27a*. Oncotarget. 2013 Sep;4(9):1388-98.
REF 5 miR-24-3p and miR-27a-3p promote cell proliferation in glioma cells via cooperative regulation of MXI1.Int J Oncol. 2013 Feb;42(2):757-66.
REF 6 miR-27a regulates cisplatin resistance and metastasis by targeting RKIP in human lung adenocarcinoma cells.Mol Cancer. 2014 Aug 16;13:193.
REF 7 MiR-27a targets sFRP1 in hFOB cells to regulate proliferation, apoptosis and differentiation.PLoS One. 2014 Mar 13;9(3):e91354.
REF 8 MicroRNA miR-27 Inhibits Adenovirus Infection by Suppressing the Expression of SNAP25 and TXN2. J Virol. 2017 May 26;91(12). pii: e00159-17.

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