miRNA General Information
miRNA Mature ID hsa-miR-483-5p
miRNA Stemloop AC MI0002467
miRNA Stemloop ID hsa-mir-483
Sequence aagacgggaggaaagaagggag
TTD Target(s) Regulated by This miRNA Extracellular signal-regulated kinase 1 (ERK1) Clinical trial Target Target Info [1]
Notch-3 receptor (NOTCH3) Clinical trial Target Target Info [2]
Transforming protein RhoA (RHOA) Discontinued Target Target Info [3]
Activated leukocyte cell adhesionmolecule (ALCAM) Clinical trial Target Target Info [4]
Protein(s) Regulated by This miRNA Creatine kinase B-type Regulated Protein [5]
Protein FAM160B2 Regulated Protein [6]
Serum response factor Regulated Protein [7]
References
REF 1 MiR-483-5p suppresses the proliferation of glioma cells via directly targeting ERK1. FEBS Lett. 2012 May 7;586(9):1312-7.
REF 2 Characterization of microRNA profile in human cumulus granulosa cells: Identification of microRNAs that regulate Notch signaling and are associated with PCOS. Mol Cell Endocrinol. 2015 Mar 15;404:26-36.
REF 3 miR-125a-3p and miR-483-5p promote adipogenesis via suppressing the RhoA/ROCK1/ERK1/2 pathway in multiple symmetric lipomatosis. Sci Rep. 2015 Jul 7;5:11909.
REF 4 miR-483-5p promotes invasion and metastasis of lung adenocarcinoma by targeting RhoGDI1 and ALCAM. Cancer Res. 2014 Jun 1;74(11):3031-42.
REF 5 Extracellular metabolic energetics can promote cancer progression.Cell. 2015 Jan 29;160(3):393-406.
REF 6 Retinoic acid induced 16 enhances tumorigenesis and serves as a novel tumor marker for hepatocellular carcinoma.Carcinogenesis. 2012 Dec;33(12):2578-85.
REF 7 MiR-483-5p controls angiogenesis in vitro and targets serum response factor.FEBS Lett. 2011 Oct 3;585(19):3095-100.

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