miRNA General Information
miRNA Mature ID hsa-miR-491-3p
miRNA Stemloop AC MI0003126
miRNA Stemloop ID hsa-mir-491
Sequence cuuaugcaagauucccuucuac
TTD Target(s) Regulated by This miRNA Cyclin-dependent kinase 6 (CDK6) Successful Target Target Info [1]
Multidrug resistance protein 1 (ABCB1) Clinical trial Target Target Info [2]
Insulin-like growth factor-binding protein 2 (IGFBP2) Literature-reported Target Target Info [3]
References
REF 1 Transcriptome-wide identification of RNA-binding protein and microRNA target sites by PAR-CLIP. Cell. 2010 Apr 2;141(1):129-41.
REF 2 Atorvastatin attenuation of ABCB1 expression is mediated by microRNA miR-491-3p in Caco-2 cells. Eur J Pharm Sci. 2016 Oct 10;93:431-6.
REF 3 Two mature products of MIR-491 coordinate to suppress key cancer hallmarks in glioblastoma. Oncogene. 2015 Mar 26;34(13):1619-1628.

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