miRNA Details
| miRNA General Information | |||||
|---|---|---|---|---|---|
| miRNA Mature ID | hsa-miR-648 | ||||
| miRNA Stemloop AC | MI0003663 | ||||
| miRNA Stemloop ID | hsa-mir-648 | ||||
| Sequence | aagugugcagggcacuggu | ||||
| TTD Target(s) Regulated by This miRNA | O-6-methylguanine-DNA-alkyltransferase (MGMT) | Clinical trial Target | Target Info | [1] | |
| Endothelin-1 (EDN1) | Literature-reported Target | Target Info | [2] | ||
| References | |||||
| REF 1 | In human glioblastomas transcript elongation by alternative polyadenylation and miRNA targeting is a potent mechanism of MGMT silencing. Acta Neuropathol. 2013 May;125(5):671-81. | ||||
| REF 2 | MicroRNA 648 Targets ET-1 mRNA and is cotranscriptionally regulated with MICAL3 by PAX5. Mol Cell Biol. 2015 Feb;35(3):514-28. | ||||
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