miRNA Details
| miRNA General Information | |||||
|---|---|---|---|---|---|
| miRNA Mature ID | hsa-miR-873-5p | ||||
| miRNA Stemloop AC | MI0005564 | ||||
| miRNA Stemloop ID | hsa-mir-873 | ||||
| Sequence | gcaggaacuugugagucuccu | ||||
| TTD Target(s) Regulated by This miRNA | Multidrug resistance protein 1 (ABCB1) | Clinical trial Target | Target Info | [1] | |
| Cyclin-dependent kinase 3 (CDK3) | Clinical trial Target | Target Info | [2] | ||
| Protein(s) Regulated by This miRNA | SRC kinase signaling inhibitor 1 | Regulated Protein | [3] | ||
| References | |||||
| REF 1 | MicroRNA-873 mediates multidrug resistance in ovarian cancer cells by targeting ABCB1. Tumour Biol. 2016 Aug;37(8):10499-506. | ||||
| REF 2 | MiR-873 regulates ER transcriptional activity and tamoxifen resistance via targeting CDK3 in breast cancer cells. Oncogene. 2015 Jul 23;34(30):3895-907. | ||||
| REF 3 | miR-873 induces lung adenocarcinoma cell proliferation and migration by targeting SRCIN1. Am J Transl Res. 2015 Nov 15;7(11):2519-26. | ||||
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