Target General Information
Target ID T13017 Target Info
Target Name Syndecan-1 (SDC1)
Synonyms SYND1; SDC; CD138
Target Type Clinical trial Target
Gene Name SDC1
Biochemical Class Peptide translocating syndecan
UniProt ID
Targeted Antigens of CAR-T Cell Therapy
CAR T-Cell Therapy Drug(s) CART-138 cells Drug Info Phase 1/2 Multiple myeloma [1]
CART-138 cells Drug Info Phase 1/2 Multiple myeloma [2]
CD138 CAR T cells Drug Info Phase 1/2 Multiple myeloma [3]
CAR138 T Cells Drug Info Phase 1 Multiple myeloma [4]
CAR-T cells targeting CD138 Drug Info Clinical trial Multiple myeloma [5]
References
REF 1 ClinicalTrials.gov (NCT01886976) Treatment of Chemotherapy Refractory Multiple Myeloma by CART-138
REF 2 ClinicalTrials.gov (NCT03196414) Study of CART-138/BCMA Therapy for R/R Multiple Myeloma
REF 3 ClinicalTrials.gov (NCT03271632) Multi-CAR T Cell Therapy in the Treatment of Multiple Myeloma
REF 4 ClinicalTrials.gov (NCT03672318) Study of ATLCAR.CD138 Cells for Relapsed/Refractory Multiple Myeloma
REF 5 ClinicalTrials.gov (NCT03473496) CAR-T Cells Therapy in Relapsed/Refractory Multiple Myeloma

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