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Target General Information |
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Target ID |
T91435 |
Target Info
|
Target Name |
Neurotrophic tyrosine kinase ROR2 (ROR2) |
Synonyms |
receptor tyrosine kinase like orphan receptor 2; neurotrophic tyrosine kinase, receptor-related 2; Tyrosine-protein kinase transmembrane receptor ROR2; NTRKR2; BDB1; BDB |
Target Type |
Clinical trial Target |
Gene Name |
ROR2 |
Biochemical Class |
Kinase |
UniProt ID |
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Targeted Antigens of CAR-T Cell Therapy |
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CAR T-Cell Therapy Drug(s) |
CCT301-38 (targeting ROR2) |
Drug Info
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Phase 1/2 |
Renal cell carcinoma |
[1] |
CCT301-59 (targeting ROR2) |
Drug Info
|
Phase 1/2 |
Renal cell carcinoma |
[1] |
References |
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REF 1 |
ClinicalTrials.gov (NCT03393936) Safety and Efficacy of CCT301 CAR-T in Adult Subjects With Recurrent or Refractory Stage IV Renal Cell Carcinoma
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