Target Validation Information
TTD ID T06559
Target Name HER4 messenger RNA (ERBB4 mRNA)
Type of Target
Literature-reported
Drug Potency against Target CL-387785 Drug Info IC50 = 12 nM [1]
References
REF 1 Tyrosine kinase inhibitors. 19. 6-Alkynamides of 4-anilinoquinazolines and 4-anilinopyrido[3,4-d]pyrimidines as irreversible inhibitors of the erbB... J Med Chem. 2006 Feb 23;49(4):1475-85.

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