| Target Validation Information | |||||
|---|---|---|---|---|---|
| TTD ID | T24836 | ||||
| Target Name | Vitamin K-dependent protein C (PROC) | ||||
| Type of Target |
Successful |
||||
| Drug Potency against Target | RPR-118071 | Drug Info | Ki = 7000 nM | [1] | |
| RPR-120844 | Drug Info | Ki = 2400 nM | [1] | ||
| References | |||||
| REF 1 | Design and structure-activity relationships of potent and selective inhibitors of blood coagulation factor Xa. J Med Chem. 1999 Sep 9;42(18):3557-71. | ||||
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