Target Validation Information
TTD ID T51120
Target Name Thyroid peroxidase (TPO)
Type of Target
Successful
Drug Potency against Target Methimazole Drug Info IC50 = 100 microM [1]
References
REF 1 Methimazole and propylthiouracil increase cellular thyroid peroxidase activity and thyroid peroxidase mRNA in cultured porcine thyroid follicles. Thyroid. 1999 May;9(5):513-8.

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