| Target Validation Information | |||||
|---|---|---|---|---|---|
| TTD ID | T55293 | ||||
| Target Name | Integrin alpha-2 (ITGA2) | ||||
| Type of Target |
Clinical trial |
||||
| Drug Potency against Target | 3-(3-(benzamido)-5-nitrobenzamido)propanoic acid | Drug Info | IC50 = 32 nM | [1] | |
| 3-(3-(carbamoyl)benzamido)-3-phenylpropanoic acid | Drug Info | IC50 = 1 nM | [1] | ||
| 3-(3-(carbamoyl)benzamido)propanoic acid | Drug Info | IC50 = 9 nM | [1] | ||
| References | |||||
| REF 1 | Derivatives of 7-amino-1,2,3,4-tetrahydroisoquinoline and isophthalic acids as novel fibrinogen receptor antagonists. Bioorg Med Chem Lett. 2006 Oct 15;16(20):5294-7. | ||||
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