Target Validation Information
TTD ID T70680
Target Name Solute carrier family 22 member 8 (SLC22A8)
Type of Target
Successful
Drug Potency against Target 3R14S-OCHRATOXIN A Drug Info Ki = 6200 nM [1]
ADIPATE Drug Info Ki = 410 nM [1]
AMINOHIPPURIC ACID Drug Info Ki = 9400 nM [1]
FLUORESCEIN Drug Info Ki = 3000 nM [1]
GLUTARATE Drug Info Ki = 6700 nM [1]
HEPTANOATE Drug Info Ki = 16700 nM [1]
References
REF 1 Structural variation governs substrate specificity for organic anion transporter (OAT) homologs. Potential remote sensing by OAT family members. J Biol Chem. 2007 Aug 17;282(33):23841-53.

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