Target Validation Information
TTD ID T72515
Target Name Interleukin 1 receptor type 1 (IL1R1)
Type of Target
Successful
Drug Potency against Target Anakinra Drug Info IC50 = 1.935 nM [1]
References
REF 1 IL-1 receptor accessory protein-Ig/IL-1 receptor type II-Ig heterodimer inhibits IL-1 response more strongly than other IL-1 blocking biopharmaceutical agents. J Clin Immunol. 2011 Jun;31(3):455-64.

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