Target Validation Information
TTD ID T99402
Target Name Metabotropic glutamate receptor 4 (mGluR4)
Type of Target
Literature-reported
Drug Potency against Target Drug Info Ki = 3400 nM [1]
(2S,1'R,2'S)-2-(2'-phosphonocyclopropyl)glycine Drug Info Ki = 7400 nM [1]
L-AP4 Drug Info Ki = 160 nM [1]
References
REF 1 Synthesis and preliminary pharmacological evaluation of the four stereoisomers of (2S)-2-(2'-phosphono-3'-phenylcyclopropyl)glycine, the first clas... Bioorg Med Chem. 2007 May 1;15(9):3161-70.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.