Target Information
Target General Information | Top | |||||
---|---|---|---|---|---|---|
Target ID |
T09266
(Former ID: TTDI02439)
|
|||||
Target Name |
Adiponectin receptor (ADIPOR)
|
|||||
Synonyms |
Progestin and adipoQ receptor family member; PAQR; Adiponectin receptor protein
Click to Show/Hide
|
|||||
Gene Name |
ADIPOR1; ADIPOR2
|
|||||
Target Type |
Literature-reported target
|
[1] | ||||
Function |
Receptor for globular and full-length adiponectin (APM1), an essential hormone secreted by adipocytes that acts as an antidiabetic. Probably involved in metabolic pathways that regulate lipid metabolism such as fatty acid oxidation. Mediates increased AMPK, PPARA ligand activity, fatty acid oxidation and glucose uptake by adiponectin. Has some high-affinity receptor for globular adiponectin but low-affinity receptor for full-length adiponectin.
Click to Show/Hide
|
|||||
UniProt ID | ||||||
Sequence |
MSSHKGSVVAQGNGAPASNREADTVELAELGPLLEEKGKRVIANPPKAEEEQTCPVPQEE
EEEVRVLTLPLQAHHAMEKMEEFVYKVWEGRWRVIPYDVLPDWLKDNDYLLHGHRPPMPS FRACFKSIFRIHTETGNIWTHLLGFVLFLFLGILTMLRPNMYFMAPLQEKVVFGMFFLGA VLCLSFSWLFHTVYCHSEKVSRTFSKLDYSGIALLIMGSFVPWLYYSFYCSPQPRLIYLS IVCVLGISAIIVAQWDRFATPKHRQTRAGVFLGLGLSGVVPTMHFTIAEGFVKATTVGQM GWFFLMAVMYITGAGLYAARIPERFFPGKFDIWFQSHQIFHVLVVAAAFVHFYGVSNLQE FRYGLEGGCTDDTLL Click to Show/Hide
|
|||||
HIT2.0 ID | T44BWE ; T97VB6 |
References | Top | |||||
---|---|---|---|---|---|---|
REF 1 | Adiporon, an adiponectin receptor agonist acts as an antidepressant and metabolic regulator in a mouse model of depression. Transl Psychiatry. 2018 Aug 16;8(1):159. |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.