Target Information
Target General Information | Top | |||||
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Target ID |
T64102
(Former ID: TTDNR00747)
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Target Name |
Serum-and glucocorticoid-inducible kinase SGK (SGK)
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Synonyms |
Serum/glucocorticoid-regulated kinase; Serine/threonine-protein kinase Sgk; SGK
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Gene Name |
SGK1; SGK2; SGK3
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Target Type |
Literature-reported target
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Function |
Invovled in ion channel and transporter regulation, regulation of cell volume, cell proliferation and apoptosis, memory formation, transcription and metabolism.
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BioChemical Class |
Kinase
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UniProt ID | ||||||
Sequence |
MTVKTEAAKGTLTYSRMRGMVAILIAFMKQRRMGLNDFIQKIANNSYACKHPEVQSILKI
SQPQEPELMNANPSPPPSPSQQINLGPSSNPHAKPSDFHFLKVIGKGSFGKVLLARHKAE EVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLVGLHFSFQTADKLYFVLDYIN GGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHIVLTD FGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSR NTAEMYDNILNKPLQLKPNITNSARHLLEGLLQKDRTKRLGAKDDFMEIKSHVFFSLINW DDLINKKITPPFNPNVSGPNDLRHFDPEFTEEPVPNSIGKSPDSVLVTASVKEAAEAFLG FSYAPPTDSFL Click to Show/Hide
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HIT2.0 ID | T85E55 |
Target Poor or Non Binders | Top | |||||
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Target Poor or Non Binders |
References | Top | |||||
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REF 1 | Second AKT: the rise of SGK in cancer signalling. Growth Factors. 2010 Dec;28(6):394-408. |
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