TTD | Drug: D08HFG

Drug General Information
Drug ID	D08HFG
Former ID	DIB019287
Drug Name	compound 18
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[531180]
Structure		Download 2D MOL
Formula	C15H13N5O
InChI	InChI=1S/C15H13N5O/c16-14(21)10-8-12(11-6-7-18-15(17)20-11)19-13(10)9-4-2-1-3-5-9/h1-8,19H,(H2,16,21)(H2,17,18,20)
InChIKey	VOQXQYXTZZHYBF-UHFFFAOYSA-N
PubChem Compound ID	24809764
PubChem Substance ID	49756559, 57124658, 85202070, 123088777, 123108542, 137516515, 138296855, 180418933, 227440917, 247532070, 249565871
Target and Pathway
Target(s)	TAO kinase 1	Target Info	Inhibitor	[531180]
	Cell division protein kinase 9	Target Info	Inhibitor	[531180]
	CDC7 protein kinase	Target Info	Inhibitor	[531180]
KEGG Pathway	Transcriptional misregulation in cancer
NetPath Pathway	EGFR1 Signaling PathwayNetPath_7:TGF_beta_Receptor Signaling Pathway
Reactome	SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
WikiPathways	Cardiac Hypertrophic Response
	Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
	Host Interactions of HIV factors
	HIV Life Cycle
	IL-9 Signaling Pathway
	RNA Polymerase II Transcription
	MicroRNAs in cardiomyocyte hypertrophy
References
Ref 531180	Cdc7 kinase inhibitors: 5-heteroaryl-3-carboxamido-2-aryl pyrroles as potential antitumor agents. 1. Lead finding. J Med Chem. 2010 Oct 28;53(20):7296-315.
Ref 531180	Cdc7 kinase inhibitors: 5-heteroaryl-3-carboxamido-2-aryl pyrroles as potential antitumor agents. 1. Lead finding. J Med Chem. 2010 Oct 28;53(20):7296-315.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.

Drug Information