Drug Information

Drug General Information
Drug ID
DX0F7C
Drug Name
4'-[(3H-Imidazol-4-ylmethyl)-amino]-[1,1';2',1'']terphenyl-3-carboxylic acid 22 (FTI-2195)
Synonyms
CHEMBL55893
Indication Discovery agent Investigative [1587926]
Formula
C23H19N3O2
Canonical SMILES
OC(=O)c1cccc(c1)c2ccc(NCc3c[nH]cn3)cc2c4ccccc4
InChI
InChI=1S/C23H19N3O2/c27-23(28)18-8-4-7-17(11-18)21-10-9-19(25-14-20-13-24-15-26-20)12-22(21)16-5-2-1-3-6-16/h1-13,15,25H,14H2,(H,24,26)(H,27,28)
InChIKey
ZUQWNRDEMRFTQP-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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