Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX0GAP
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| Drug Name |
3-[2-Cyano-2-(2-diphenylacetylamino-3-m-tolyl-propionylamino)-ethoxymethyl]-benzoic acid
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| Synonyms |
CHEMBL336228
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C35H33N3O5
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| Canonical SMILES |
Cc1cccc(C[C@H](NC(=O)C(c2ccccc2)c3ccccc3)C(=O)N[C@@H](COCc4cccc(c4)C(=O)O)C#N)c1
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| InChI |
InChI=1S/C35H33N3O5/c1-24-10-8-11-25(18-24)20-31(38-34(40)32(27-13-4-2-5-14-27)28-15-6-3-7-16-28)33(39)37-30(21-36)23-43-22-26-12-9-17-29(19-26)35(41)42/h2-19,30-32H,20,22-23H2,1H3,(H,37,39)(H,38,40)(H,41,42)/t30-,31+/m1/s1
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| InChIKey |
NLBSRGTVALONBM-JSOSNVBQSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin L | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| References | |||||
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