Drug Information

Drug General Information
Drug ID
DX0KM4
Drug Name
2-(4-{2-[4-((R)-3,10-Dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperidin-1-yl]-2-oxo-ethyl}-piperidin-1-yl)-2-oxo-acetamide
Synonyms
CHEMBL89304
Indication Discovery agent Investigative [1587926]
Formula
C28H31Br2ClN4O3
Canonical SMILES
NC(=O)C(=O)N1CCC(CC(=O)N2CCC(CC2)[C@H]3c4ncc(Br)cc4CCc5cc(Cl)cc(Br)c35)CC1
InChI
InChI=1S/C28H31Br2ClN4O3/c29-20-12-19-2-1-18-13-21(31)14-22(30)24(18)25(26(19)33-15-20)17-5-9-34(10-6-17)23(36)11-16-3-7-35(8-4-16)28(38)27(32)37/h12-17,25H,1-11H2,(H2,32,37)/t25-/m1/s1
InChIKey
BZEILLJNWWUORJ-RUZDIDTESA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.