Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX0NS1
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| Drug Name |
N-[1-(2S-Ethyl-4-oxo-tetrahydro-furan-3S-ylcarbamoyl)-2-(1-methyl-cyclopentyl)-ethyl]-4-methanesulfonylamino-3-methyl-benzamide
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| Synonyms |
CHEMBL479461
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C24H35N3O6S
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| Canonical SMILES |
CC[C@@H]1OCC(=O)[C@H]1NC(=O)[C@H](CC2(C)CCCC2)NC(=O)c3ccc(NS(=O)(=O)C)c(C)c3
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| InChI |
InChI=1S/C24H35N3O6S/c1-5-20-21(19(28)14-33-20)26-23(30)18(13-24(3)10-6-7-11-24)25-22(29)16-8-9-17(15(2)12-16)27-34(4,31)32/h8-9,12,18,20-21,27H,5-7,10-11,13-14H2,1-4H3,(H,25,29)(H,26,30)/t18-,20-,21+/m0/s1
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| InChIKey |
UAEAHQWORKLQQF-SESVDKBCSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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