Drug Information

Drug General Information
Drug ID
DX0SWE
Drug Name
4-({[4-(3-Bromo-8-chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-N-cyano-piperidine-1-carboximidoyl]-amino}-methyl)-piperidine-1-carboxylic acid amide
Synonyms
CHEMBL440732
Indication Discovery agent Investigative [1587926]
Formula
C28H31BrClN7O
Canonical SMILES
NC(=O)N1CCC(C\\N=C(\\NC#N)/N2CCC(=C3c4ccc(Cl)cc4CCc5cc(Br)cnc35)CC2)CC1
InChI
InChI=1S/C28H31BrClN7O/c29-22-13-21-2-1-20-14-23(30)3-4-24(20)25(26(21)33-16-22)19-7-11-37(12-8-19)28(35-17-31)34-15-18-5-9-36(10-6-18)27(32)38/h3-4,13-14,16,18H,1-2,5-12,15H2,(H2,32,38)(H,34,35)
InChIKey
KJBINAWDNVGVJU-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.