Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX1CA8
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| Drug Name |
6-[4-(4-Acetyl-piperazin-1-yl)-phenoxymethyl]-7-(2-cyclohexyl-ethyl)-7H-pyrrolo[2,3-d]pyrimidine-2-carbonitrile
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| Synonyms |
CHEMBL481170
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C28H34N6O2
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| Canonical SMILES |
CC(=O)N1CCN(CC1)c2ccc(OCc3cc4cnc(nc4n3CCC5CCCCC5)C#N)cc2
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| InChI |
InChI=1S/C28H34N6O2/c1-21(35)32-13-15-33(16-14-32)24-7-9-26(10-8-24)36-20-25-17-23-19-30-27(18-29)31-28(23)34(25)12-11-22-5-3-2-4-6-22/h7-10,17,19,22H,2-6,11-16,20H2,1H3
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| InChIKey |
SZVFURKQYHRIBV-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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