Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX1HZ8
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| Drug Name |
2-(cyclohexylmethyl)-N-(4-(methylsulfonyl)-1-(4-(trifluoromethoxy)phenylamino)butan-2-yl)-4-morpholino-4-oxobutanamide
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| Synonyms |
CHEMBL493231
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C27H40F3N3O6S
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| Canonical SMILES |
CS(=O)(=O)CCC(CNc1ccc(OC(F)(F)F)cc1)NC(=O)C(CC2CCCCC2)CC(=O)N3CCOCC3
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| InChI |
InChI=1S/C27H40F3N3O6S/c1-40(36,37)16-11-23(19-31-22-7-9-24(10-8-22)39-27(28,29)30)32-26(35)21(17-20-5-3-2-4-6-20)18-25(34)33-12-14-38-15-13-33/h7-10,20-21,23,31H,2-6,11-19H2,1H3,(H,32,35)
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| InChIKey |
BVNIEHLGKBDVDH-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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