Drug Information

Drug General Information
Drug ID
DX1J6U
Drug Name
(R)-2-(2-(benzo[c][1,2,5]thiadiazole-4-sulfonamido)-4-chlorobenzamido)-3-phenylpropanoic acid
Synonyms
CHEMBL570518
Indication Discovery agent Investigative [1587926]
Formula
C22H17ClN4O5S2
Canonical SMILES
OC(=O)[C@@H](Cc1ccccc1)NC(=O)c2ccc(Cl)cc2NS(=O)(=O)c3cccc4nsnc34
InChI
InChI=1S/C22H17ClN4O5S2/c23-14-9-10-15(21(28)24-18(22(29)30)11-13-5-2-1-3-6-13)17(12-14)27-34(31,32)19-8-4-7-16-20(19)26-33-25-16/h1-10,12,18,27H,11H2,(H,24,28)(H,29,30)/t18-/m1/s1
InChIKey
LALFDMSTRARYCO-GOSISDBHSA-N
Target and Pathway
Target(s) Gastrin/cholecystokinin type B receptor Target Info [1587926]
Cholecystokinin receptor type A Target Info [1587926]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Gastric acid secretionhsa04020:Calcium signaling pathway
Insulin secretion
Pancreatic secretion
PANTHER Pathway CCKR signaling map ST
PathWhiz Pathway Gastric Acid Production
Reactome Peptide ligand-binding receptors
G alpha (q) signalling events
Gastrin-CREB signalling pathway via PKC and MAPKR-HSA-375276:Peptide ligand-binding receptors
WikiPathways GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
Secretion of Hydrochloric Acid in Parietal Cells
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
GPCRs, OtherWP455:GPCRs, Class A Rhodopsin-like
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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