Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX1QZE
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| Drug Name |
(S)-N-(1-(2-(5-chloroindolin-1-yl)ethylamino)-4-methyl-1-oxopentan-2-yl)-3-methylbenzamide
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| Synonyms |
CHEMBL379230
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C24H30ClN3O2
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| Canonical SMILES |
CC(C)C[C@H](NC(=O)c1cccc(C)c1)C(=O)NCCN2CCc3cc(Cl)ccc23
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| InChI |
InChI=1S/C24H30ClN3O2/c1-16(2)13-21(27-23(29)19-6-4-5-17(3)14-19)24(30)26-10-12-28-11-9-18-15-20(25)7-8-22(18)28/h4-8,14-16,21H,9-13H2,1-3H3,(H,26,30)(H,27,29)/t21-/m0/s1
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| InChIKey |
XGEOFLZCNAEENF-NRFANRHFSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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