Drug Information
| Drug General Information | |||||
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| Drug ID |
DX1SE7
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| Drug Name |
(S)-N-(3-(3-(1,3,4-thiadiazol-2-yl)phenyl)-1-(cyanomethylamino)-1-oxopropan-2-yl)-3-tert-butyl-1-methyl-1H-pyrazole-5-carboxamide
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| Synonyms |
CHEMBL549378
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C22H25N7O2S
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| Canonical SMILES |
Cn1nc(cc1C(=O)N[C@@H](Cc2cccc(c2)c3nncs3)C(=O)NCC#N)C(C)(C)C
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| InChI |
InChI=1S/C22H25N7O2S/c1-22(2,3)18-12-17(29(4)28-18)20(31)26-16(19(30)24-9-8-23)11-14-6-5-7-15(10-14)21-27-25-13-32-21/h5-7,10,12-13,16H,9,11H2,1-4H3,(H,24,30)(H,26,31)/t16-/m0/s1
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| InChIKey |
ACGFKLACOBPYKQ-INIZCTEOSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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