Drug Information

Drug General Information
Drug ID
DX1TIY
Drug Name
N-[(Isopropyl-phenyl-carbamoyl)-methyl]-N-phenyl-2-(3-phenyl-ureido)-acetamide
Synonyms
CHEMBL421778
Indication Discovery agent Investigative [1587926]
Formula
C26H28N4O3
Canonical SMILES
CC(C)N(C(=O)CN(C(=O)CNC(=O)Nc1ccccc1)c2ccccc2)c3ccccc3
InChI
InChI=1S/C26H28N4O3/c1-20(2)30(23-16-10-5-11-17-23)25(32)19-29(22-14-8-4-9-15-22)24(31)18-27-26(33)28-21-12-6-3-7-13-21/h3-17,20H,18-19H2,1-2H3,(H2,27,28,33)
InChIKey
HONVEEQHGVXUMK-UHFFFAOYSA-N
Target and Pathway
Target(s) Gastrin/cholecystokinin type B receptor Target Info [1587926]
Cholecystokinin receptor type A Target Info [1587926]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Gastric acid secretionhsa04020:Calcium signaling pathway
Insulin secretion
Pancreatic secretion
PANTHER Pathway CCKR signaling map ST
PathWhiz Pathway Gastric Acid Production
Reactome Peptide ligand-binding receptors
G alpha (q) signalling events
Gastrin-CREB signalling pathway via PKC and MAPKR-HSA-375276:Peptide ligand-binding receptors
WikiPathways GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
Secretion of Hydrochloric Acid in Parietal Cells
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
GPCRs, OtherWP455:GPCRs, Class A Rhodopsin-like
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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